| 1986-1993 | Medical School, University of Essen |
| 1991-1993 | Doctoral thesis (Dr. med.), Essen Medical School with Prof. Dr. H. Esche, Dept. of Molecular Biology |
| 1993-1997 | Resident in Pediatrics, University Children s Hospital Essen |
| 1997-2000 | Postdoctoral Fellow (DKH + Wolfson Career Development Grant), The Children s Hospital of Philadelphia |
| 1998 | Evans Prize from the "Advances in Neuroblastoma Research" (ANR) International Symposium, Philadelphia |
| 2000-2002 | Clinical Fellow and Junior Group Leader, Dept. of Pediatric Hematology/Oncology, University Hospital Essen |
| 2000 | Dr. Odile Schweisguth Prize from the International Society for Pediatric Oncology (SIOP) |
| 2001 | Kind-Philipp Prize for Pediatric Oncology from the German Society for Pediatric Oncology and Hematology (GPOH) |
| Young Investigator Award, American Assoc. for Cancer Research (AACR) |
| 2003-2004 | Senior Attending Physician (Oberärztin) and Group Leader, Dept. of Pediatric Hematology/Oncology, University Hospital Essen |
| 2004 | Habilitation in Pediatrics and Pediatric Oncology |
| 2004-2008 | Professor of Pediatric Oncology Research (C3) and Deputy Director, Dept of Pediatric Hematology/Oncology, University Hospital Essen |
| 2004-2013 | Head, Pediatric Cancer Research, University Hospital Essen |
| 2007-2013 | Director, WTZ Essen (Comprehensive Cancer Center) |
| 2008-2013 | Full Professor of Pediatrics and Director, Dept. of Pediatric Hematology and Oncology, University Hospital Essen |
| 2009-2011 | Executive MBA in International Hospital and Health Care Management, Frankfurt School of Finance and Management |
| since 2013 | Full Professor of Pediatrics and Director, Dept. of Pediatric Oncology / Hematology, Campus Virchow-Klinikum, Charité University Medicine, Berlin |
| Endowed Einstein Chair in Pediatric Oncology, Charité University Medicine |
| 1978-1984 | Medical School University of Bonn |
| 1984 | Doctorate from the University of Bonn |
| Assistant in Clinical Biochemistry, University of Bonn |
| 1984-1985 | Fellowship of the German Academic Exchange Service, Reproductive Medicine at the Eastern Virginia Medical School, Norfolk, VA |
| 1985 | Foreign Medical Graduate Examination in the Medical Sciences (FMGEMS) USA |
| 1988 | Federal Licensing Examination (FLEX) USA |
| 1985-1992 | Resident in Ob/Gyn, University Womens Hospital of Bonn |
| 1989 | Practical training course in molecular biology at the EMBL, Heidelberg |
| 1989-1991 | Fellowship,German Research Community, Molecular Oncology, Mount Sinai Hospital New York |
| since 1992 | Specialist in Ob/Gyn |
| 1994-1997 | Habilitation fellowship of the DFG at the University of Bonn |
| since 1997 | Head of the Centre for Familial Breast and Ovarian Cancer at the Universities Cologne/Bonn supported by German Cancer Aid |
| 1998-2003 | Assistant professor at the Dept. Ob/Gyn (C2), University Womens Hospital Bonn |
| 1997 | Postdoctoral lecturing qualification (Habilitation), University of Bonn |
| since 2003 | Full professor at the Dept. Ob/Gyn (C3), Div. Molecular Gyneco-Oncology, University of Cologne |
| since 2012 | Director of the Center for Familial Breast and Ovarian Cancer |
| 1975-1981 | Medical school, University of Freiburg, Germany |
| 1981 | Final medical exam, University of Freiburg, Germany |
| Medical license, Landesärztekammer Südbaden |
| 1982-1984 | Residency training in neuropathology, University of Freiburg |
| 1984 | MD degree, University of Freiburg |
| 1984-1987 | Postdoctoral fellow, Department of Pathology, University of California, San Diego |
| 1987-1989 | Residency training in neuropathology, Institute of Neuropathology, Department of Pathology, University of Zürich |
| 1989-1992 | Senior resident in neuropathology, Institute of Neuropathology, Department of Pathology, University of Zürich / Switzerland |
| 1992-2003 | Professor of Neuropathology, Head of the Department of Neuropathology, University of Bonn Medical Center |
| 1994-2003 | Head, German Brain Tumor Reference Center, Bonn |
| 1994-1999 | Member, Executive Committee, University of Bonn Medical Center |
| 1994-2003 | Coordinator, Collaborative Research Center for Clinical & Molecular Neurobiology, University of Bonn |
| 1995-2003 | Chairman, BONFOR research committee, University of Bonn Medical Center |
| 1996-2004 | Elected member Pathology Board, German Research Council (DFG) |
| Member of the Medical Advisory Board, German Cancer Aid |
| 1997 | Appointment as Head of the Department of Neuropathology, Charité Medical Center, Humboldt University Berlin (declined) |
| 1998-1999 | President, German Society of Neuropathology and Neuroanatomy |
| 2000-2004 | Head of the Review Board Theoretical Medicine, German Research Council |
| 2001-2003 | Vice-Coordinator, Transregional Collaborative Research Center Mesial Temporal Lobe Epilepsies, Universities of Bonn, Berlin, Freiburg and Magdeburg 2001-2012 Review Panel Member, NCCR Neural Plasticity & Repair, Zürich |
| 2001 | Election to the German Life Science Academy Leopoldina |
| 2002-2003 | Chief Scientific Officer, Neuroscience Technology Platform LIFE & BRAIN, University of Bonn Medical Center |
| Chairman of the Board, Competence Network for Stem Cell Research, State of Northrhine Westfalia |
| 2004-2015 | Chairman and Scientific Member, Management Board Deutsches Krebsforschungszentrum, Heidelberg |
| 2004-2014 | Chairman of the Advisory Board, Deutsche Krebshilfe |
| since 2004 | Member of the Executive Board, Deutsche Krebshilfe |
| Member Board of Trustees, Meyenburg Foundation, Heidelberg |
| 2004-2010 | Coordinator, Brain Tumor Network, National Genome Research Network 2 |
| 2004-2012 | Member Scientific Advisory Board and Board of Trustees, German Institute for Nutrition Research, Potsdam |
| 2004-2008 | Member Scientific Advisory Board, University Medical Center Hamburg-Eppendorf |
| since 2004 | Member Board of Trustees, Heinrich F.C. Behr Foundation |
| since 2005 | Member Board of Trustees, Alois Hirdt-Erben und Wieland-Stiftung |
| 2005-2012 | Coordinator of Biomedical Research, Helmholtz Association |
| since 2006 | Member Board of Trustees, Gemeinnützige Hertie-Stiftung, Frankfurt |
| 2007-2014 | Member Board of Trustees , Hertie-Institut für Klinische Hirnforschung, Tübingen |
| since 2007 | Member Board of Trustees, Georg-Speyer-Haus, Frankfurt |
| 2007-2012 | Vice President, Helmholtz Association |
| 2007-2011 | Member, Advisory Board Molecular Diagnostics, Siemens Medical Solutions |
| Member, Founding Committee, German Center for Neurodegenerative Diseases |
| since 2009 | Member, Scientific Committee Hansen Family Award Bayer |
| since 2010 | Member, Scientific Advisory Board, Institute Gustave Roussy, Villejuif/Paris |
| Member, International Scientific Advisory Board, INCA Paris |
| Member, Scientific Advisory Board, Bayer Healthcare Berlin |
| Member, Scientific Advisory Board, University of Cologne |
| since 2011 | Coordinator, German Consortium for Translational Cancer Research |
| since 2012 | Member of the European Academy of Tumor Immunology |
| since 2014 | Member of Supervisory Board, BAYER AG |
| since 2015 | Chair of SAB of National Sequencing Center |
| President of the Helmhotz Association in Berlin |
| since 2016 | Member of the Supervisory Board, Berlin Institute of Health |
